(A) Selected human single-cell transcriptome profiles from HCL and other public datasets were utilized to train and validate gPRINT. The human single-cell data encompasses 159,302 cells from 26 ...

Bulk RNA sequencing provides cost-effective, population-level transcriptome insights, but averaging gene expression across all cells can mask important biological variability and obscure cellular ...

Analyzing a person’s gene expression requires mapping their RNA landscape to a standard reference to gain insight into the degree to which genes are “turned on” and perform functions in the body. But ...

Combining tissue profiling with whole transcriptome spatial analysis and high-plex protein co-detection enables a deeper, more holistic understanding of tissue organization "The continued expansion of ...

Analysis of scRNA-seq data from primate embryoid bodies highlights the value of cross-species comparisons for identifying and characterizing cell types, as marker genes can evolve fast.

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

Precision Treatment of Patients With GI Cancer Using Pre-emptive DPYD Genotyping/Phenotyping Plus Pharmacokinetic-Guided Dosing of 5-Fluorouracil Primary PCa biopsy samples underwent ...

In a recent study published in the International Journal of Molecular Sciences, researchers conducted a transcriptome-wide association study (TWAS) to understand the genetic basis of the chronic ...