Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...

A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...

Experiments from the 1940s established a key tenet of genetics—mutagenesis occurs randomly across the genome. New research, however, suggests that mutations may be less random than originally thought.