Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Scientists have found new genetic causes for diabetes in babies—in a part of the genome that has historically been overlooked ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Typically, female mouse embryos with two X chromosomes develop ovaries because a gene called Sox9 is suppressed. In male ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Clues to the genetic code’s origin may be hidden in tiny protein fragments, revealing a synchronized and highly structured path to life’s earliest molecular systems.

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...