Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

In new research, scientists at the Department of Energy's SLAC National Accelerator Laboratory, in collaboration with ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Pulmonary fibrosis is a progressive interstitial lung disease characterized by excessive extracellular matrix deposition, ...

A technique that transforms immune cells into cancer-seeking bloodhounds may overcome a roadblock that has hampered ...

Scientists finally cracked the mystery of why infections kill your appetite—and it all starts with hidden gut cells talking to your brain.

Sex differences in the prevalence, severity, and disability associated with pain are well documented in both clinical and preclinical research. Despite ...